Abstract
Worldwide, breast cancer is the most frequently diagnosed life-threatening cancer in women. This cross sectional study was done to assess the presenting features of locally advanced breast cancer. The mean age was 42.6 years with standard deviation 9.56, 86% were house wife, 53.5% were illiterate, 16% were postmenopausal and 75.8% had BMI of 20Kg/m2. Ninety one point five percent had menarche at or above 12 years of age and 26.6 % had history of using hormonal contraceptives. Tobacco user and positive family history were found in 21.2% and 5.35% of the cases. 84% were presented with only lump and 16% with both lump and ulceration. Right breast was involved in 51.1%. About 37% cases presented on 3rd month of their symptoms. Around 71.2% patients presented with lump >5cm in diameter, axillary lymph nodes were palpable in 81% and fixed in 31% of patients. Around Sixty three percent of patients were in stage IIIA. Still a large fraction of patients present with advanced stage with varied presentation, sometimes surgeons face difficulties to offer the treatment. Proper awareness, early presentation and early detection give them the opportunity to receive the best treatment. BSMMU J 2021; 14(4): 148-151
Highlights
Advanced breast cancer (LABC) refers to a term that includes a heterogeneous group of diseases
Women included were the locally advanced breast cancer patients sent for neoadjuvant chemotherapy from surgical oncology outdoor department
Ninety four (94) patients with locally advanced breast cancer were included in the study
Summary
The global importance of cancer is unquestionable, considered the second cause of death worldwide. The incidence of different cancers had increased both in developed and developing countries as a result of increasing exposure to risk factors and life expectancy[1]. Breast cancer is one of the most common cancers with more than 1,300,000 cases and 450,000 deaths each year worldwide[2]. In less-developed countries it is the most frequently diagnosed life-threatening cancer and leading cause of cancer death in women[3]. Advanced breast cancer (LABC) refers to a term that includes a heterogeneous group of diseases. Data from the Surveillance, Epidemiology and End Results (SEER) program of National Cancer Institute indicated that approximately 7% of breast cancer patients have stage III disease at diagnosis[4]. Though we have no central data base or cancer registry, studies show that 52.6% of breast cancer patient presented as locally advanced disease in Bangladesh[5]. Advanced breast cancer at presentation was common in developing countries[6]
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