Presentation and Treatment of a Patient with Three Primary Head and Neck Cancers: A Case Report

Abstract

Triple primary head and neck carcinoma is a rare occurrence. In our case, a patient presented with early stage triple primary head and neck squamous cell carcinoma (HNSCC). Early stage HNSCC is usually treated with surgery and/or radiation. However, treatment of triple primary head and neck malignancies is not clearly defined in the literature, and although our patient presented with early stage lesions, our multidisciplinary team recommended concomitant chemoradiotherapy. Our patient subsequently had resolution of disease after completion of therapy but was lost to long-term follow-up.