Present status of diagnostic tests for rheumatic fever.

Abstract

Article1 November 1952PRESENT STATUS OF DIAGNOSTIC TESTS FOR RHEUMATIC FEVERMACLYN MCCARTY, M.D.MACLYN MCCARTY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-5-1027 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe diagnosis of rheumatic fever offers no difficulties in those cases which present the classic clinical picture. Due to the great variability of the disease, however, only a minority of the total cases fall into this category, and it is frequently necessary to look to the laboratory for assistance in establishing the diagnosis. In view of this fact, it is unfortunate that none of the many tests employed provides an unequivocal answer concerning the occurrence of the disease. At the present time, no laboratory test is available which is comparable in its significance to the serologic tests for syphilis or...Bibliography1. Todd EW: Antihemolysin titers in haemolytic streptococcal infections and their significance in rheumatic fever, Brit. J. Exper. Path. 13: 248, 1932. Google Scholar2. Jones TD: The diagnosis of rheumatic fever, J. A. M. A. 126: 481, 1944. CrossrefGoogle Scholar3. KleinLevinsonRosenblum RISAD: Weltmann reaction and sedimentation rate during rheumatic fever in childhood, Am. J. Dis. Child. 59: 48, 1940. Google Scholar4. KelleyGoodMcQuarrie VCRAI: Serum mucoproteins in children in health and disease with special reference to rheumatic fever, Pediatrics 5: 824, 1950. MedlineGoogle Scholar5. GoodGlick RAD: Mucolytic enzyme systems. IX. Non-specific hyaluronidase inhibitor in rheumatic fever, J. Infect. Dis. 86: 38, 1950. CrossrefMedlineGoogle Scholar6. AndersonMcCarty HCM: Determination of C-reactive protein in the blood as a measure of the activity of the disease process in acute rheumatic fever, Am. J. Med. 8: 445, 1950. CrossrefMedlineGoogle Scholar7. Jacox RF: The activating effect of calcium on a bactericidal substance for Bacillus subtilis in human serum, J. Exper. Med. 92: 101, 1950. CrossrefMedlineGoogle Scholar8. JacoxGale RFRG: The reaction of human serum with a quaternary ammonium salt: results of a serial study in acute rheumatic fever, J. Lab. and Clin. Med. 37: 728, 1951. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*From the Symposium on Rheumatic Fever presented at the Thirty-third Annual Session of the American College of Physicians, Cleveland, Ohio, April 25, 1952.From the Hospital of The Rockefeller Institute for Medical Research, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe career of Maclyn McCartyAntistreptolysin levels in normal infants and young childrenErkrankungen des EndokardFr�hdiagnose post-operativer Komplikationen mit Hilfe des C-reaktiven ProteinsA STUDY OF STREPTOCOCCAL INFECTION IN A SCHOOL POPULATION: LABORATORY METHODOLOGY*‡GEORGES WERNER, Ph.D., DAVID CORNFELD, M.D., JOHN P. HUBBARD, M.D., F.A.C.P., GEOFFREY RAKE, M.D., F.A.C.P.Observations on the treatment of rheumatic fever with salicylate, ACTH and cortisone. II. Combined salicylate and corticoid therapy and attempts at rebound suppressionC-Reactive protein in pregnancyRHEUMATISM AND ARTHRITIS REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (ELEVENTH RHEUMATISM REVIEW)* Part IIWILLIAM D. ROBINSON, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D., F.A.C.P.Laboratory aids in the diagnosis of rheumatic fever and in evaluation of disease activityThe C-reactive protein determination as a measure of rheumatic activityThe Differential Diagnosis of Fevers: The Present Status of the Problem of Fever of Unknown OriginAureomycin in the Prophylaxis of Rheumatic Fever 1 November 1952Volume 37, Issue 5Page: 1027-1034KeywordsFallsLaboratory testsResearch laboratoriesRheumatic feverSyphilis ePublished: 1 December 2008 Issue Published: 1 November 1952 PDF downloadLoading ...