Abstract
A comparative study concerning the presence of the red-yellow iron pigment has been carried out on mice of various coat color phenotypes. Pigment was always present in both agouti as well as in non-agouti animals although in different amounts (agouti hairs contained twice as much rhodanin as non-agouti hairs). The genetic control of rhodanin biosynthesis and distribution in pigment cells, as well as its role in hair color is thoroughly discussed. A gene interaction pattern occurring at the phenotypic level among expressions of the different alleles of the A, B, D and P loci is inferred from experimental results. This does not rule out the possibility of an identity between and the old phaeomelanin.
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