Abstract
Multi transfusion of blood and its components in cardio- vascular surgeries still remains a standard practice despite various advances in blood saving practices. Amongst the complications of blood transfusion, the formation of alloantibodies and autoantibodies against red blood cell antigens is one problem that frequently confounds the blood transfusion services [1]. Among such antibodies are alloantibodies against Rhesus (Rh) blood group antigens. Fifty-eight antigens belonging to Rh system have been discovered till date [2]. However the common problems revolve around five principal antigens that are—D, E, e, C and c and their corresponding antibodies, anti-D, anti-E, anti-e, anti-C and anti-c. Anti-c is clinically the most important Rh antibody after anti-D [2]. Anti-c is an important cause of delayed hemolytic transfusion reactions (DHTR) and hemolytic disease of fetus and newborn (HDFN) [2]. One such case of anti-c seen in our transfusion services is presented below.
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