Year-end Sale % OFF 
Abstract
The concentrations of norepinephrine (NE), dopamine (DA) and its metabolites DOPAC and HVA, and serotonin (5-HT) and its metabolite 5-HIAA, were quantified in the rat vestibule. For this purpose, homogenates of vestibules, of albino and pigmented rats, were analyzed using HPLC with electrochemical detection. Vestibules of pigmented rats showed higher DOPAC and HVA concentrations than those of albino rats, and male pigmented rats also showed significantly more DA than male albino rats. These results could indicate that the rate of DA metabolism in vestibules was higher in pigmented than in albino rats. The vestibular concentrations of NE and 5-HT did not differ significantly between the two strains. In contrast, 5-HIAA concentration was higher in vestibules of pigmented rats than in those of albino rats, suggesting an increased 5-HT metabolism for the former strain. Differences in monoamine concentrations between the two sexes of the same strain were scarce. Only, a higher HVA concentration in vestibules of females could indicate a higher DA metabolism.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
