Abstract

Although the presence of androgenic substances in the placenta is mentioned by several authors, these fail to make any specific citation to the original work, and an examination of the more common indices is no more encouraging.Siebka1 examined 2 placentae following operative abortion and failed to find any androgens in the 4-5-month-old organs. If there is any positive evidence of the occurrence of androgens in the placenta, it has not found its way into the current literature.The purpose of this study was to determine whether or not the presence of androgens in the placenta could be demonstrated.Three male and 3 female full term placentae were secured, washed as free of blood as possible and extracted according to the Gallagher and Koch method. The extracts were assayed both on capons and by the colorimetric methods.The colorimetric assay∗ indicated the presence of one international unit in 60.7 g of male placenta, and one I.U. in 69.4 g of female placenta. The capon test showed for the male placentae o...

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