Preselection of lung cancer cases using FGFR1 mRNA and gene copy number for treatment with ponatinib.

Terry L Ng,D Ross Camidge,Theresa A Boyle,Dexiang Gao,Hui Yu,Derek Smith,Scott Leedy,Emily R York,Lynn Heasley,Fred R Hirsch

doi:10.1200/jco.2018.36.15_suppl.12095

Preselection of lung cancer cases using FGFR1 mRNA and gene copy number for treatment with ponatinib.

Terry L Ng, D Ross Camidge + Show 8 more

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https://doi.org/10.1200/jco.2018.36.15_suppl.12095

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Journal: Journal of Clinical Oncology	Publication Date: May 20, 2018
Citations: 2

Affiliation: University of Colorado Cancer Center, University of Colorado Anschutz Medical Campus, Colorado School of Public Health, International Craniofacial Institute

#FGFR1 mRNA #FGFR1 Amplification + Show 8 more

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12095Background: NSCLC and SCLC cell line data suggested high FGFR1 mRNA levels and FGFR1 amplification (FGFR1-AMP) could predict sensitivity to FGFR TKIs. Overlap with KRAS mutations did not precl...

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