Abstract
Results. The 531 children included in the study received 2 190 prescriptions during the study period. Of these 446 (20.4%) were for unlicensed use and 470 (21.5%) for off-label use. The most common form of unlicensed medicine use was modification of licensed dosage forms (e.g. crushing of tablets to make suspensions), while the most frequent pattern of off-label use was using doses other than those recommended for the paediatric age categories. Conclusion. Unlicensed and off-label medicines are widely used for children in the centres studied. Further research on this subject is recommended in other parts of Nigeria and Africa.
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