Abstract
Objective To early detect and prevent the development of chronic kidney disease (CKD) in children investigating and analyzing the incidence of urine abnormality in healthy preschool children at Liwan District, Guangzhou. Methods The routine samples of midstream morning urine of 6-7 years old healthy preschool children were collected from 2013 to 2017, and were analyzed by dry-chemistry test paper method and urinary sedimentanalytical method. Results 13 992 children were investigated in this study. The total abnormality rate of urine was 13.68% (1 914 cases), and was 6.97%(5 23/7 504) in the boys and 21.40%(1 391/6 488) the girls. In the boys, 64 cases (0.85%) had abnormal white blood cell ( WBC), 438 cases (5.84%) urine red blood cell( RBC), and 30 cases (0.40%) proteinuria; and in the girls, 842 (12.98%), 582 (8.97%), and 39 (0.60%). The abnormalities of urine WBC and RBC were significantly higher in the girls than in the boys (P<0.05). There was no statistical difference in proteinuria between the boys and the girls. Conclusion The abnormality rate of urine of preschool children at Liwan District, Guangzhou was screened. There is a high abnormality rate of urine analysis in healthy children. It’s very essential to have urine screening for healthy preschool children, which can not only early detect but also intervene the occult diseases of urinary system, and it is of great significance to track the development of chronic kidney disease (CKD) in children. Key words: Urine screening; Proteinuria; Hematuresis; Leucocyturia; Chronic kidney disease(CKD); Pre-school children
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