PReS-FINAL-2252: Descriptive analysis of pediatric autoimmune neuropsychiatric disorder associated with streptococcus infection (PANDAS) in a cohort of 65 Italian patients

F Falcini,F Bertini,G Lepri,D Rigante,M Matucci Cerinic

doi:10.1186/1546-0096-11-s2-p242

Abstract

PANDAS includes neuropsychiatric symptoms, mainly obsessive-compulsive disorder (OCD) or tics, temporally associated with an immune-mediated response to group A β-hemolytic Streptococcus (GAS) infections, which suddenly start before puberty and display remitting/relapsing course.

Highlights

Pediatric Rheumatology European Society (PReS)-FINAL-2252: Descriptive analysis of pediatric autoimmune neuropsychiatric disorder associated with streptococcus infection (PANDAS) in a cohort of 65 Italian patients
PANDAS includes neuropsychiatric symptoms, mainly obsessive-compulsive disorder (OCD) or tics, temporally associated with an immune-mediated response to group A b-hemolytic Streptococcus (GAS) infections, which suddenly start before puberty and display remitting/ relapsing course
Descriptive analysis of a cohort of Italian patients with PANDAS.Between may 2009 - may 2013 we observed 65 pts (50 M, 15 F, mean age: 100.8 ± 32,9 months) with OCD and/or tics starting before puberty, associated with a previous GAS infection

Summary

Introduction

PANDAS includes neuropsychiatric symptoms, mainly obsessive-compulsive disorder (OCD) or tics, temporally associated with an immune-mediated response to group A b-hemolytic Streptococcus (GAS) infections, which suddenly start before puberty and display remitting/ relapsing course

Methods

Findings

Conclusion