Abstract
Patients with autoinflammatory syndromes may present a clinical course characterized by recurrent, episodic manifestations (such as fever, skin rash or visceral involvement) or they may show a continuous, unremitting disease course with persistent clinical manifestations. Patients with certain diseases, such as CAPS or Blau syndrome, usually present this type of course.
Highlights
Patients with autoinflammatory syndromes may present a clinical course characterized by recurrent, episodic manifestations or they may show a continuous, unremitting disease course with persistent clinical manifestations
Autoinflammatory syndrome was defined as the presence of a chronic, systemic disease with no evidence of malignancy, infection or autoimmunity
Genetic analysis was performed in different locations
Summary
Patients with autoinflammatory syndromes may present a clinical course characterized by recurrent, episodic manifestations (such as fever, skin rash or visceral involvement) or they may show a continuous, unremitting disease course with persistent clinical manifestations. Patients with certain diseases, such as CAPS or Blau syndrome, usually present this type
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