Abstract
Treatment of juvenile idiopathic arthritis (JIA) has changed dramatically since the introduction of biologics in 1999. Because of more insight in the cytokines involved in JIA the number of available biologic agents increased. Together with the introduction of these new drugs, new insights in the optimal treatment of JIA indicate that earlier and more aggressive therapy is associated with better outcomes. Whether these developments with regard to biologic treatment have resulted in better patients' outcomes in daily practice is not yet reported.
Highlights
Treatment of juvenile idiopathic arthritis (JIA) has changed dramatically since the introduction of biologics in 1999
Because of more insight in the cytokines involved in JIA the number of available biologic agents increased
343 non-systemic and 86 systemic JIA patients started at least 1 biologic agent between 1999 and 2010
Summary
Treatment of juvenile idiopathic arthritis (JIA) has changed dramatically since the introduction of biologics in 1999. Because of more insight in the cytokines involved in JIA the number of available biologic agents increased. Together with the introduction of these new drugs, new insights in the optimal treatment of JIA indicate that earlier and more aggressive therapy is associated with better outcomes. Whether these developments with regard to biologic treatment have resulted in better patients’ outcomes in daily practice is not yet reported
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