Abstract
Chronic Musculoskeletal Pain (MSP) in children can be due to various non-inflammatory conditions, such as the benign joint hypermobility syndrome (BJHS) or idiopathic MSP (IMSP). MSP heavily influences patient's quality of life and is often misdiagnosed or included in the vast category of unspecific MSP. A careful differential diagnosis and knowledge of possible risk factors are needed to properly approach a child/adolescent with osteoarticular symptoms.
Highlights
Chronic Musculoskeletal Pain (MSP) in children can be due to various non-inflammatory conditions, such as the benign joint hypermobility syndrome (BJHS) or idiopathic MSP (IMSP)
Aim of the study was to evaluate the persistence of osteoarticular symptoms in a cohort of schoolchildren with MSP followed for three years and to analyze the main risk factors for it, with particular attention to the role of the pubertal stage
Pre-pubertal patients have a higher probability of recovering from MSP than the pubertal ones; vice versa pubertal subjects are at high risk for suffering from MSP during early adulthood, especially females with BJHS
Summary
Aim of the study was to evaluate the persistence of osteoarticular symptoms in a cohort of schoolchildren with MSP followed for three years and to analyze the main risk factors for it, with particular attention to the role of the pubertal stage. We evaluated the immunological profile and its relation with MSP and puberty. A laboratory test was performed to determine the presence of ANA, ENA and antidsDNA
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