Abstract
Preparative gas chromatographic enantiomer separation was achieved by using a packed column with heptakis(2,6-di-O-methyl-3-O-pentyl)-β-cyclodextrin (2,6-Me-3-Pe-β-CD) as a chiral stationary phase. Depending on the selectivity factor up to milligram amounts of almost pure enantiomers or at least enantiomeric mixtures, sufficiently enriched to determine the sign of optical rotation, could be obtained with only one injection of a racemate. This technique may be very useful for stereochemical assignments, for attaining pure enantiomers for bioassays, pharmacokinetic and metabolic studies and investigations of fragrance and flavour compounds.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
