Abstract

Polysaccharides are the main active components of Grifola umbellate , most of which are β-glucans with (1→3)-β-glucose main chain and (1→6)-β-glucose side chain structures. Grifola umbellate polysaccharides (GUPs) have antioxidant, immune regulation, anti-tumor, and other effects. But so far, for different types of GUPs, the relationship between their structures and functions has not explicitly been classified and summarized. Herein, the extraction, isolation and purification, structures, derivatization, biological activities and applications of GUPs were reviewed. It provided a reference for the research and development of GUPs in the future. • Preparation of GUPs was summed up. • The structure-function relationship of GUPs was discussed. • The application of GUPs was summarized and elaborated.

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