Preparation of Triazole Gold(III) Complex as an Effective Catalyst for the Synthesis of E‐α‐Haloenones

Abstract

AbstractThe pyridyltriazole ligand was prepared and applied as a new ligand system for the coordination towards gold(III) cations. The resulting complex showed excellent stability and effective catalytic reactivity for the Meyer–Schuster rearrangement of propargyl alcohols and sequential allene halogenation, giving α‐haloenones with excellent yields and good E/Z selectivity. More importantly, by using this new gold(III) catalytic system, the challenging α‐chloroenone substrates were synthesized in good yields for the first time. This work also permits the avoidance of preparing of acetate derivatives as required in the case of Au(I) catalysts and validates that the triazole gold(III) complex is an effective new catalyst for alkyne activation.magnified image