Abstract
Preparation of substituted alkoxypyridines via directed metalation and metal-halogen exchange
Highlights
Various alkoxypyridines are found in pharmaceutical agents,1-3 electronic materials,4 liquid crystals,5 organometallic complexes,6-8 and oligomers
Tetrahydrofuran (THF), ether, and toluene were distilled from sodium/benzophenone ketyl prior to use
X-ray spectral analysis was performed at North Carolina State University using Apex2 diffractometer
Summary
Various alkoxypyridines are found in pharmaceutical agents,1-3 electronic materials,4 liquid crystals,5 organometallic complexes,6-8 and oligomers.9 They have been used as synthetic building blocks for natural products and medicinal agents.10 Over the years, for use in our alkaloid total synthesis projects,11 several derivatives of alkoxypyridines have been prepared using directed metalation and metal-halogen exchange reactions.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
