Abstract

The current pandemic brought to our attention the need for continuous research and development on the fight against pathogens. The use of derivatives of starch nanocrystals (SNC) with antimicrobial activities offers a good alternative to conventional antimicrobial agents since they can be sourced from readily available, biodegradable, and biocompatible raw materials. In this study, starch nanocrystals were prepared by acid hydrolysis and oxidized using hydrogen peroxide. The resulting oxidized starch nanocrystals showed inhibitory effect against E. coli. FTIR analysis showed that the antimicrobial activity could be due to the introduction of carbonyl groups in the starch chain. Due to the versatility of starch nanocrystals, other derivatives with improved antimicrobial activity or other tailored properties could also be developed.

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