Preparation of Silica‐Coated Lanthanum–Strontium Manganite Particles with Designable Curie Point, for Application in Hyperthermia Treatments

Abstract

Silica‐coated lanthanum–strontium manganite particles with La0.76Sr0.24MnO3+δ stoichiometric formula, exhibiting Curie temperature at ∼40°C, were prepared by using a traditional solid‐state method of synthesis of magnetic ceramic particles, followed by milling and a low‐temperature coating procedure in an aqueous alcoholic alkali medium. The properties of the obtained material establish it as a potential candidate for self‐regulated power‐absorbing and temperature‐controlling materials in hyperthermia treatments. Moreover, core‐comprising LaSr–manganites with different stoichiometries, ranging from La0.5Sr0.5MnO3+δ to LaMnO3+δ, were synthesized, with magnetic and structural properties examined thereof. Herein reported findings can potentially be used in the preparation of silica‐coated magnetic particles with designable Curie temperature, offering a wide range of possibilities of adapting the material to practical instrumental setups in drug delivery and hyperthermia treatments.