Abstract
A very simple method for the preparation of several active N-chloro compounds that have extensive applications in organic synthesis, industry, and medicine has been developed. Tetrachloroglycolurils, chloramine-T, N-chlorosaccharin, N-chlorosuccinimide, N-chlorophthalimide, N,N′-dichlorophenobarbital, and N,N′-dichlorobarbital were synthesized by chlorination with trichloroisocyanuric acid under mild reaction conditions at room temperature. This method is clean, fast, and efficient; the yields are also good to excellent.
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