Abstract
A facile organic-silica hybrid monolith was prepared by a thiol-ene click reaction of polyhedral oligomeric silsesquioxane methacryl substituted (POSS-MA) with 1,4-bis(mercaptoacetoxy) butane (BMAB) using toluene and dodecanol as a porogenic system. The effects of the ratio of POSS-MA-BMAB and porogenic solvents and click reaction temperature on the morphology, permeability and column performance of the resulting POSS-BMAB hybrid monoliths were studied in detail. A uniform monolithic network with a high porosity was obtained. The POSS-BMAB hybrid monolith exhibited good permeability and high thermal and mechanical stability. A series of test compounds, including alkylbenzenes, polycyclic aromatic hydrocarbon, phenols and, anilines were used to evaluate the retention behaviors of the POSS-BMAB hybrid monolith in capillary liquid chromatography. The prepared POSS-BMAB hybrid monolith exhibited typical reversed-phase chromatographic behavior toward neutral solutes. The minimum plate height of this hybrid monolith was determined as 12.6 and 13.7 μm for thiourea and benzene, respectively. These results demonstrate that thiol-ene click chemistry can provide a facile and robust approach for the preparation of a POSS-based hybrid monolith.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
