Abstract
AbstractSeveral isoxazolidines, derived from the 1,3‐dipolar cycloaddition of α,β‐hexenolides to cyclic nitrones, were converted into the corresponding piperidine‐ and pyrrolidine‐oxepinones by reduction of the nitrogen−oxygen bond. The potential of the resulting amino alcohols as synthetic precursors of polycyclic alkaloids was explored. These intermediates provide a new access to the 1‐azabicyclo[5.3.0]decane core of the Stemona alkaloids. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
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