Preparation of gonadotrophin and growth hormone from human pituitaries for clinical use.

Abstract

SUMMARY A procedure for extracting both gonadotrophin and growth hormone from acetone-dried pituitary powder in a form suitable for clinical use is described. Gonadotrophin is extracted first and fractionated by ethanolic precipitation; growth hormone is then extracted from the residues by a modification of Raben's procedure. The yields and potency of the products are given with particular emphasis on their activities in man. The economy of the preparation of gonadotrophin and growth hormone from human pituitaries is discussed.