Abstract

In this study, the fluorescence ethosomes (ES-QDs) composed of hydrophilic CdTe fluorescent clusters (quantum dots, QDs) were prepared. The prepared ES-QDs with even particle size were obtained by extruding the vesicles through polycarbonate membrane filters and were characterized by TEM SEM HPPS and photoluminescence spectra. Their in vitro experiments to penetrate into human skin scar were performed by using the Franz diffusion cell. Results showed that the prepared ES-QDs not only have the properties of ethosome to penetrate the skin scar tissues but also have the fluorescence labeling properties of the quantum dots. The prepared ES-QDs have potential clinical application in therapy of skin scar.

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