Abstract
One of the most attractive and versatile approaches for the stereoselective synthesis of β-amino acids involves the conjugate addition of an amine nucleophile to α,β-unsaturated carboxylic acid derivatives. This chapter summarizes the key advances achieved in this area from 1997 to 2004 with emphasis on enantioselective conjugate additions, including: Conjugate Addition of Alkyl or Aromatic Amines Addition of Hydroxylamine to Enoates Conjugate Addition of Azide Conjugate Addition of Carbon-Nucleophiles
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