Abstract
Photothermal therapy (PTT) is a new treatment, and photoacoustic (PA) imaging-guided PTT has aroused extensive attention recently. Poly-2-phenyl-benzobisthiazole (PB) is a new type of conjugated polymer with good biocompatibility and excellent photothermal properties similar to single-walled CNT. However, the poor hydrophilicity of PB limits its application in biomaterials. In this work, chitosan-Cu(II) network structure was first constructed, and then the Cu(II) in-situ initiated the polymerization of aminobenzenedithiophenol and terephthalonitrile to obtain chitosan/PB composite. The excellent hydrophilicity of chitosan-based nanoparticle has successfully improved the water solubility of the obtained nanoprobe PB/CS. Additionally, PB/CS has an excellent PA signal. Thus, a simple and convenient nanosystem was fabricated and applied for PA imaging-guided PTT.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
