Abstract
An efficient and high-yielding procedure has been developed for the synthesis of a set of fifteen 2,2-diphenyl-l,3,2-ox-azaborolidin-5-ones, through the reaction of the corresponding α-amino acid with diphenyl borinic acid under alkaline conditions (pH 7.5-8). It is of note that these compounds showed potent cytotoxic activity on K-562 and HCT-15 cell lines.
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