Abstract
AbstractHigh radiochemical yields of 14C‐labeled adenine nucleotides (AMP, 4.6%; ADP, 15.5% and ATP, 59.5%) could be obtained by growing the cells of Brevi bacterium ammoniaqenes in the presence of 14C‐adenine. The specific radioactivity of the adenine nucleotides almost reached that of 14C‐adenine indicating negligible dilution of the label. The procedure is conveninet and especially suited for commercial preparation of the radiolabeled nucleotides directly from labeled adenine. Preliminary results indicate that the organism could also be used for the preparation of radiolabeled quanine nucleotides.
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