Abstract

This work included prepare of hetero atom compounds Ra1-Ra5from the interaction of prepared azomethines with anhydride compound. Azomethine compounds were prepared by condensation reaction. A number of new hetero atom compounds were prepared by acid-catalyzed Cycloaddition-reaction in anhydrous THF under reflux conditions. The formation of hetero ring has been achieved by Cycloaddition. The melting point, 1H-NMR, FT-IR and 13C-NMRspectroscopies technique were used to identified the final products. Biological activity of the prepared hetero compounds Ra1-Ra5 evaluated on E. Coli and S. aureus.

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