Abstract

Two novel water-soluble morin hydrate (MH) complexes, composed of a hydrophobic MH core and hydrophilic cyclodextrin shell, were prepared and systematically investigated in both aqueous solution and the solid state by means of UV–Vis spectroscopy, 1H NMR, 2D NMR (ROESY), SEM, FT-IR, DSC, TGA, and XRD analysis. The characterization information resulting from these investigations revealed that the MH/cyclodextrin inclusion complexes formed by the MH with CD in 1:1 stoichiometry, and demonstrated satisfactory water solubility. The MH/cyclodextrin complexes still maintained antibacterial activity in vitro test against Staphylococcus aureus bacteria.

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