Abstract
Multi-walled Carbon nanotubes (MWCNTs) have been extensively explored for a variety of biomedical and tissue engineering applications. Their high surface area provides tunable multiple attachment sites for acquiring appropriate biological and biomechanical properties. Despite, the cytotoxicity of MWCNTs is dubious with or without surface functionalization. In the present study, two different kinds of multi-walled carbon nanotubes (MWCNTs) in the presence of cobalt oxide (Co3O4) and nickel oxide (NiO) nanoparticles have been prepared through a simplistic and effective method, and thus, the Co3O4/MWNT and NiO/MWNT structures are loaded to chitosan in methanol solution at 65°C. Results upon the synthesis and structural characterization were obtained by Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), and transmission electron microscopy (TEM), respectively. It has been shown that the tuned functionalized MWCNTs are able to reduce cytotoxic effects and improve biocompatibility and be more appropriate for potential future clinical applications.
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