Abstract
Preparation and thermally-induced self-assembly behaviour of elastin-like peptide side-chain polymer-gold nanoparticle (ESP-GNP) hybrids
Highlights
Metallic nanomaterials continue to serve as a crucial platform for many advanced technologies in therapy, diagnostics, sensing and catalysis
Elastin-like peptides (ELPs), which are composed of repeating pentapeptide sequences of the form VPGXG where X represents any naturally occurring amino acid other than proline, undergo a reversible conformational transition from random coil to -spiral upon increasing solution temperature beyond a transition temperature[10]
We show that the transition temperature of peptide-modified gold nanoparticles (GNPs) can be modulated by preparing ELP peptide side-chain polymers (ESPs) of different length, and subsequently conjugating these polymers to GNP surfaces
Summary
Preparation and thermally-induced self-assembly behaviour of elastin-like peptide side-chain polymer-gold nanoparticle (ESP-GNP) hybrids. Cameron∗b,c a Department of Chemistry, Durham University, South Rd., Durham, DH1 3LE, U.K. b Department of Materials Science and Engineering, Monash University, 22 Alliance Lane, Clayton, Victoria. 3800, Australia c School of Engineering, University of Warwick, Coventry, CV4 7AL, U.K. Dedicated to Professor Philip Hodge, recognising his contributions to polymers in synthesis over 45 years
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