Preparation and spectroanalytical studies of two new azo compounds derived from the drug methyl-4-amino benzoate

Abstract

Two new azo compounds were prepared from the drug methyl-4-amino benzoate with pyridoxine hydrochloride ( B6 ) (A1) and with ventolin (salbutamol sulphate ) (A2). The characterization of azo compounds have been described by I.R., mass spectra and visible spectroscopic techniques. At various pH values ( 2-12 ) , the electronic spectra of these azo compounds were investigated in terms of acid-base properties ,which includes establishing isobestic points and determination of protonation and ionization constants. The effect of solvents of different polarities on the electronic spectra was the subject of the other research. The azo compound ( A2) has been used in a variety of applications for nitrite determination.