Abstract
A Strontium-doped titanium oxide coating was successfully prepared on a TA4 substrate with one-step microarc oxidation (MAO) technology. Then bioactivity of the coating was performed with the inducation test of bone-like apatite formation immersed in simulated body fluid (SBF). The biological activity of the coating was evaluated with cell culture experiments, and its corrosion resistance was characterized with electrochemical tests in the SBF. The composition and morphology of the coatings before and after SBF immersion were characterized with X-ray diffraction (XRD), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). The results showed that the coating had a rough porous structure, which was mainly composed of anatase, rutile and Ti phases. The SBF immersion test showed that abundant 3D micro nanopore structures were formed on the surface of the porous titanium oxide coatings, which enabled the coatings to exhibit good apatite nucleation ability. Faster precipitation of bone-like apatite by MAO-Sr coatings in SBF. Finally, in the biological compatibility test, compared with TA4, the contact angle between the MAO-Sr coating and SBF solution was lower, and the proliferation ability of bone marrow stromal cells (BMSCs) in the biological coating was stronger, indicating the good biocompatibility of the coating.
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