Abstract
Copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and poly(ethylene glycol) methacrylate (PEGMA) and isopropanol as a diluent were prepared by photopolymerization. The swelling kinetics, mechanical properties, drug release behaviors, and the interaction between various drugs and the present copolymeric gels were investigated in this study. The results showed that the addition of PEGMA could effectively increase the equilibrium water content and the diffusion coefficient and penetration velocity of water though the gels. Although Young's modulus increased with the increase of PEGMA content, the resulting gels had smaller elongation and more brittle characteristics. The drug release behavior was strongly dependent on the interaction between the present copolymeric gels and drugs such as caffeine, crystal violet (CV), phenol red, and vitamin B12.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
