Preparation and Characterization of PLA Film/3D Printing Composite Scaffold for Tissue Engineering Application

Abstract

Three-dimensional (3D) printing technology provides an effective alternative for tissue engineering scaffold. In this paper, a composite scaffold composed of polylactic acid (PLA) film and 3D printing scaffold was fabricated which could provide structural and mechanical support for tissue application. The effects of PLA film/3D printing composite scaffold on scaffold morphology, average diameter, pore diameter, mechanical properties, themal conductivity, electrical conductivity, and surface hydrophilicity were characterized. PLA film/3D printing composite scaffold had larger thickness, better mechanical and thermal conductivity properties in comparison with pure PLA film and 3D printed scaffold. These results suggested that composite scaffold with relatively good overall performance could be a potential candidate for tissue engineering application.