Preparation and Characterization of Novel disubstituted 1, 3-Oxazepine-tetra-one from Schiff bases reaction with 3-methylfuran-2, 5-dione and 3-Phenyldihydrofuran-2, 5-dione

Abstract

This research includes synthesis of new heterocyclic derivatives of novel disubstituted 1,3- oxazepine-tetra-one from Schiff bases reaction with 3-methylfuran-2,5-dione and 3-phenyldihydrofuran-2,5-dione. Schiff bases [A1-A5] were synthesized by the reaction of aromatic aldehydes with primary aromatic amines, in the presence of glacial acetic acid as catalyst in absolute ethanol. The novel derivatives[A6-A10] were obtained from treatment of Schiff bases with anhydrides. The synthesized compounds were identified by TLC and via spectral methods, their (FT-IR, 1H-NMR and 13C-NMR) and measurements of some of its physical properties.