Preparation and Characterization of a Novel Rice Paste for Bone Hemostatic Biomaterial

Abstract

Bone hemostatic biomaterials were prepared with different compositions of rice starch (RS) powder and glycerin-base soap. The glycerin soap was composed of liquid glycerol:KOH:stearic acid by aqueous solution method. RS powders (10, 20, 40, and 60 wt %) was added to the purified glycerin soap. The physical properties and degradation of the obtained samples were evaluated. The samples were characterized by scanning electron microscopy (SEM), degree of swelling (DS), moisture content and degradation. An addition of RS powder increased absorbability property, the smoothness, whiteness and could be smear easily on the surface. The results of optimized condition have shown the samples of 20 wt% RS powder had the highest DS of 0.91 ± 0.25 for 90 minutes, the moisture content of 0.43 ± 0.21 % and the degradability of 69.95± 1.50 % for 48 hours. Our results concluded that the samples were sufficient physical properties for use as substitute, and more degradable than bone wax.