Abstract

The increasing need for a new tissue engineering scaffold has revived interest in bacterial cellulose (BC) and its water holding capacity (WHC), porosity, and biocompatibility. Bacterial cellulose was produced using Gluconacetobacter xylinus, and bacterial cellulose film (BCF) was prepared by lyophilization. To obtain macroporous bacterial cellulose (MBCS), BCF was rinsed with poly(ethylene glycol) (PEG-400), adjusted to 0.25% BC concentration, and freeze-dried. The objective of this study to compare BCF and MBCS in terms of porosity, in vitro degradation, WHC, and the cell viability of mouse fibroblast cell line (NIH-3T3). The results showed that the MBCS has great potential for tissue engineering.

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