Preparation and Assignment of Radioactive Labelled Compounds for Dental Research

Abstract

The application of radioactive tracers gives a powerful tool in opening a new reseach field in dental science. However, in almost all experiments with radioactive tracers, it is not very easy to interpret the results obtained accurately because of the lack of definite chemical form of radioactive materials used.The present authors have engaged in the study of preparations, syntheses and assignments of radioactive materials which might be useful for radioactive tracer works both in fundamental and clinical dental researches. In the present paper the preparation of dental cement liquids labelled with radioactive phosphorus (32P) is described with some studies on their chemical and radiochemical purities.Dental cements, i. e. zinc phosphate cement, silicate cement and others, are frequently used in routine dental practice, as a very important material in operative and prosthetic dentistry. ZANDER et al. [1], GLASS and ZANDER [2] had reported that the successful use of radioactive phosphorus for investigations in the properties of dental cements. But these reports contained only a bare mention of the procedure for 32P-labelling and the chemical form of the resulted labelled cement liquids. This is the reason why the present authors have undertaked the study on the preparation of 32P-labelled dental cement liquids. The chemical forms of the labelled cement liquids are determined by means of paper chromatography.