Preparation and Application of Novel Mesoporous Silica Microsphere-Based Thin Layer Chromatography Plate

Abstract

With excellent mechanical properties and high specific surface area, mesoporous silica microspheres are widely applied in various fields. However, mesoporous silica has been relatively studied as a thin-layer chromatographic (TCL) material for preliminary separation and detection. In this study, we obtained mesoporous silica microspheres with different particle sizes and apertures by a simple synthesis method, and prepare mesoporous silica microspheres-based TCL. Excellent test results have been exhibited, the 4.5 μm mesoporous silica microspheres-based TCL exhibits better separation results in dye and fluorescent polymer separation experiments, thus expanding the application of mesoporous silica microspheres.