Abstract
Amphoteric surface active N-substituted amino acid derivatives containing long chain alkoxyl radicals and the methylmethylene, ethylene, and methylethylene radicals between amino and carboxyl groups were prepared, then their antimicrobial properties against G. positive, G. negative bacilli and fungi were determined. It was confirmed that N-substituted β-alanine derivatives showed higher antimicrobial properties than the corresponding α-alanine derivatives. The effect of side methyl group between an ammonium and a carboxylate radical was not clear.The surface tension of the N-substituted β-alanine aqueous solution was about 3035dyn/cm in the pH range from 3 to 11.
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