Preparation and antimicrobial activity of ZnO-NPs coated cotton/starch and their functionalized ZnO-Ag/cotton and Zn(II) curcumin/cotton materials

Issa M El-Nahhal,Jamil Salem,Abdelraouf Elmanama,Fawzi S Kodeh,Rawan Anbar

doi:10.1038/s41598-020-61306-6

Issa M El-Nahhal, Jamil Salem + Show 3 more

Open Access

https://doi.org/10.1038/s41598-020-61306-6

Copy DOI

Abstract

ZnO-NPs coated cotton or starched cotton fibers were successfully prepared via ultrasound irradiation. Different concentrations of soluble corn starch (1–3 starch wt.%) were used to stabilize ZnO-NPs onto the surface of cotton fabrics as entrapped species. The use of none-toxic biocompatible starch has improved the adhesion properties of the cotton fibers towards ZnO-NPs. This also enhanced the durability of ZnO-NPs onto the cotton fabrics and decreased their leaching from the surface of cotton fabrics. When 3 starch wt.% solution was used, deposition of ZnO-NP increased by 53% after 10 washing cycles. The antibacterial activity against Staphylococcus aureus and Escherichia coli increased by 50 and 21.5%, respectively. Functionalization of ZnO coated cotton with silver nanoparticles (Ag-NPs) and curcumin results in formation of ZnO-Ag/cotton and Zn(II) curcumin/cotton composites. The functionalized nanocomposites ZnO-Ag coated cotton material showed a synergistic antimicrobial behavior than that of individual ZnO/cotton material. The Zn(II) curcumin complex coated cotton showed higher antibacterial activities against both Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative) bacteria than that of the ZnO/cotton material.

Highlights

ZnO-NPs coated cotton or starched cotton fibers were successfully prepared via ultrasound irradiation
The starched cotton materials were prepared by treatment of pristine cotton with corn starch at three different concentrations (1–3 starch wt.%) at 70 °C for 5 hours, vacuum filtered and dried to obtain gelatinized starched cotton fibers
ZnO-NPs coated cotton fibers or ZnO-NPs coated starched cotton fibers were obtained by deposition of ZnO-NPs onto cotton or starched cotton fibers using the ultrasound irradiation method of the zinc oxide according to the reaction illustrated in Scheme 13,10,29

Summary

Introduction

ZnO-NPs coated cotton or starched cotton fibers were successfully prepared via ultrasound irradiation. A single step sono-enzymatic process for coating cotton medical textiles with antibacterial ZnO nanoparticles (NPs) and garlic acid(GA) was recently described to produce biocompatible fabrics with durable antibacterial properties[2]. This system showed a better fixation for ZnO onto the cotton substrate and better antimicrobial activity[2]. Common antimicrobials agents e.g. penicillin and tetracycline have been well known as antimicrobials, bacteria have become resistant to most antimicrobial agents and the main future research in antimicrobial therapy is to develop novel materials which may work as effective antimicrobials In this context, ZnO-coated cotton has been synthesized and further functionalized with silver nanoparticles and curcumin. Dehydrated nutrient agar powder, nutrient broth powder, Sabouraud Dextrose Agar (SDA), Di-Chloran Rose Bengal Chloramphenicol (DRBC) agar and Potato Dextrose Agar (PDA), were purchased from (HiMedia, India) and used to prepare culture media

Methods

Results

Conclusion