Abstract
Paralysis is not only the disabling sequel of poliomyelitis, but when it affects the muscles of respiration it is the cause of death. From the practical standpoint, therefore, treatment aims to prevent or moderate this serious feature of the disease. Paralysis, either partial or complete, is due to injury or death of nerve cells. If treatment is to succeed, then, it must be applied before nerve cell destruction has taken place. Fortunately, infantile paralysis may be diagnosed during its preparalytic stage. The increased prevalence of poliomyelitis in Massachusetts in 1927 afforded an opportunity for further testing the use of convalescent serum under fairly uniform conditions. SELECTION OF CASES FOR SERUM TREATMENT While the extent of the occurrence of abortive poliomyelitis is not known, it is generally believed that many of the mild febrile attacks occurring in the vicinity of known cases of the disease represent a generalized infection with the
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