Abstract
Preoperativno visoko senzitivni troponin T i N-terminal pro B tip natriuretskog peptida u predikciji mortaliteta u kratkom periodu posle nekardiohirurških operacija (Visoko senzitivni troponin T i N-terminal pro B tip natriuretskog peptida u predikciji mortaliteta posle nekardiohirurških operacija)
Highlights
Non-cardiac surgery is usually performed on elective basis
Neither Mangano nor Lidsky in their studies found the association between preoperative coronary artery disease (CAD) and both major cardiac events and subsequent mortality after surgical intervention[2,19], our results showed statistically significant association with fatal events in short-term follow-up
In summary, this study has shown that preoperatively increased levels of cardiac biomarkers are positively associated with short-term mortality in postoperative period after major abdominal or vascular surgery, and they can serve as important predictors of fatal events
Summary
Non-cardiac surgery is usually performed on elective basis. This type of surgery can be associated with significant cardiovascular morbidity and mortality. One of the most important predictors of complications is Coronary Artery Disease (CAD)[1,2]. When a patient with ischemic cardiac disease undergoes a high-risk surgery, the risk of cardiac complications rises almost tenfold[3]. There are powerful biomarkers that reflect myocardial injury, heart failure, valvular heart disease, as well as CAD. From a group of potential biomarkers, B-type Natriuretic Peptide (BNP) and N-Terminal Pro B-type natriuretic peptide (NT-proBNP), and troponins seem to be the most important[4, 5]
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