Abstract
The objective of this study is to investigate the complete pathological reaction of preoperative radiotherapy and chemotherapy for rectal cancer. We conducted a retrospective and explanatory study to evaluate the reaction to preoperative radiotherapy and chemotherapy in 46 patients of stage I, II and III rectal adenocarcinoma from 2006 to 2014. These patients were divided into four groups, in which 52.17% complete remission (24 cases), 15.21% moderate remission (7 cases), 6.53% minimum remission (3 cases) and 26.09% adverse reactions (12 cases). In this study, more than 50% of patients with preoperative radiotherapy and chemotherapy show complete pathological response, which may provide the possibility for patients with rectal adenocarcinoma to receive this treatment in the future, and a carefully selected group among the patients will enter the observation period.
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