Preoperative monocyte to high-density lipoprotein ratio as a predictor of survival outcome of gastric cancer patients after radical resection.

Abstract

Aim: This study aimed to verify the prognostic value of monocyte to high-density lipoprotein ratio (MHR) in gastric cancer patients after radical resection. Methods: The Cox proportional hazards model was used to determine the risk variables for survival. Results: Older age (>60years) (hazard ratio [HR]: 1.832; 95% CI:1.167-2.725; p =0.009), advanced tumor node metastasis stage (p <0.05), lymphatic invasion (HR: 1.639; 95% CI: 1.114-3.032; p <0.05), vascular invasion (HR: 2.002; 95% CI: 1.246-5.453; p =0.028) and high MHR (HR: 1.154; 95% CI: 1.062-2.315; p =0.021) were independent poor prognostic factors for gastric cancer patients after radical resection. Conclusion: Older age, advanced tumor node metastasis stage, lymphatic invasion, vascular invasion and high MHR were independent poor prognostic factors for gastric cancer patients after radical resection.