Abstract

BackgroundThere is currently no subjective, definitive evaluation method for therapeutic indication other than symptoms in aortic regurgitation. Energy loss, a novel parameter of cardiac workload, can be visualized and quantified using echocardiography vector flow mapping. The purpose of the present study was to evaluate whether energy loss in patients with chronic aortic regurgitation can quantify their subjective symptoms more clearly than other conventional metrics.MethodsWe studied 15 patients undergoing elective aortic valve surgery for aortic regurgitation. We divided the patients into symptomatic and asymptomatic groups using their admission records. We analyzed the mean energy loss in one cardiac cycle using transesophageal echocardiography during the preoperative period. The relationships between symptoms, energy loss, and other conventional metrics were statistically analyzed.ResultsThere were seven and eight patients in the symptomatic and asymptomatic groups, respectively. The mean energy loss of one cardiac cycle was higher in the symptomatic group (121 mW/m [96–184]) than in the asymptomatic group (87 mW/m [80–103]) (p = 0.040), whereas the diastolic diameter was higher in the asymptomatic group (65 mm [59–78]) than in the symptomatic group (57 mm [51–57]) (p = 0.040). There was no significant difference between the symptomatic and asymptomatic groups in terms of other conventional metrics.ConclusionsAn energy loss can quantify patients' subjective symptoms more clearly than other conventional metrics. The small sample size is the primary limitation of our study, further studies assessing larger cohort of patients are warranted to validate our findings.

Highlights

  • There is no subjective, definitive evaluation method for therapeutic indication other than presenting symptoms in aortic regurgitation (AR)

  • Our research suggests that left ventricular energy loss (EL) in chronic AR is superior to other conventional echocardiographic indices to explain pathophysiology

  • The novel point is that we investigated the relationship between EL and symptoms in patients with AR who were all in need of surgery and found that a high EL indicated patients’ subjective symptoms

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Summary

Introduction

There is no subjective, definitive evaluation method for therapeutic indication other than presenting symptoms in aortic regurgitation (AR). VFM analysis of valvular [7–10] and congenital heart disease [11, 12] can reportedly reveal and evaluate the effectiveness of the surgical treatment. As it does not require the use of contrast, this VFM technology can be used in routine clinical practice to assess ventricular vortices and predict patients’ outcome [13]. There is currently no subjective, definitive evaluation method for therapeutic indication other than symptoms in aortic regurgitation. The purpose of the present study was to evaluate whether energy loss in patients with chronic aortic regurgitation can quantify their subjective symptoms more clearly than other conventional metrics

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