Abstract

Summary A total of 60 patients were subjected to total pneumonectomy in a 6 year period at the Yale-New Haven Medical Center. A group of 20 who were submitted to preoperative x-irradiation was compared with 40 who came to operation directly with no intervening irradiation therapy. Higher operative mortality and postoperative cardiac complication rates have been demonstrated in the irradiated group than in the non-irradiated patients. There seemed to be little difference in long-term survival in the two groups. Preoperative x-ray treatment continues to be a useful modality in the management of some patients with bronchogenic carcinoma, but its use at present levels of dosage and technique does not appear routinely indicated. The authors would like to express their appreciation to Gustaf E. Lindskog, M.D., for his guidance in preparation of the manuscript and to Katherine N. Detre, M.D., for statistical help.

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